pkrrating Can Be Fun For Anyone
The interfacial residues are remarkably conserved amongst eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements exhibit that the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations help a product exactly where activating RNA serves to be a scaffold to bind many PKR monomers, raisi